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Additionally, there are prescription forms of Nicotine Replace Therapy (NRT) inhalers, nasal sprays, varenicline, and bupropion to weaken withdrawal symptoms

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Generally, activation of the acetylcholine-7nAChR signaling axis by acetylcholine or nicotine inhibits NF-B, the critical transcription factor in the activation of inflammation in different immune cells [174, 175, 177]